Discovering significant breakthroughs in fibrosis.

Our Pipeline

Insights from preclinical experiments and an intensive structure-based chemistry effort lead to the discovery of a library of covalent, reversible, small molecule dimeric calpain inhibitors. Currently, 2 molecules from this library are advancing into development.

BLD-2660

(IPF)

    

BLD-2660

(NASH)

    

BLD-0409

(formerly PAT-409)

    

BLD-2184

(Neurodegeneration)

    

Scientific Publications